Probable starting eleven:

Chelsea:
Cech, Bosingwa, Luiz, Ivanovic, Cahil, Meireles, Romeu, Malouda, Sturridge, Torres, Mata

Manchester United:
De Gea, Smalling, Ferdinand, Evans, Evra, Valencia, Giggs, Carrick, Park, Hernandez, Rooney

First about the absences. Chelsea will miss six players. Ashley Cole is suspended, John Terry is sidelined with a knee injury, while Didier Drogba and Salomon Kalou are on international duty at the African Cup of the Nations. Finally, John Obi Mikel and Ramires are injured. Manchester United will be without five players - the goalkeeper Anders Lindegaard, Anderson, Phil Jones, Darren Fletcher and Nemanja Vidic are all injured.

The absences are the key reason for my pick. Chelsea attack is not sharp at the moment. Drogba and Kalou are on international duties, while Fernando Torres is out of form. He has gone 12 matches (1,076 minutes or 17 hours and 56 minutes) in the league without scoring a single goal. That is why Chelsea failed to win against teams like Norwich or Swansea in the last two rounds. By the way, Chelsea scored only one goal on the mentioned two games.

On contrary, Manchester United is in excellent form. They are in series of three consecutive victories in Premier league and they catch Manchester City on the first place. Here are the results:

31.01. Manchester Utd - Stoke 2:0
22.01. Arsenal - Manchester Utd 1:2
14.01. Manchester Utd - Bolton 3:0

I think Manchester will win at Stamford Bridge.