Probable starting eleven:

Tottenham:
Friedel, Walker, King, Kaboul, Assou-Ekotto, Krancjar, Parker, Modric, Bale, Defoe, Adebayor

Arsenal:
Szczesny, Sagna, Mertesacker, Song, Santos, Arteta, Frimpong, Ramsey, Walcott, Van Persie, Arshavin

Arsenal is in the deepest crisis in the last 20 years. The manager Arsen Wenger is also under the big pressure and I don't see the way he can handle with that. Fabregas and Nasri departures are the main reason for the bad results. Arsenal is particularly bad on road. After the goalless draw with Newcastle in the first round, Arsenal suffered a catastrophe from Manchester United (heavy defeat of 8:2) and painful loss from Blackburn (4:3). I don't see something positive and I expect another defeat for Arsenal. Tottenham is a strong team, the players will be extremely motivated against the city rival and I believe they are able to win. Even more as Tottenham is in series of three consecutive victories in the Premier League, against Wolverhampton, Liverpool and Wigan, plus the victory in UEFA Europe League against Shamrock Rovers.

For this match both managers have some problems. Harry Redknapp will be without William Gallas, Michael Dawson and Tom Huddlestone. On other side Arsen Wenger will be without Gervinho, Laurent Koscielny, Yossi Benayoun and Johan Djourou.